Infected Granulation Tissue Transforming into Pyogenic Granuloma and Peripheral Ossifying Fibroma: A Case Report

Abstract

Objective: Granulation tissue represents a subtle 
presentation of Reactive Hyperplastic Lesions (RHLs). With 
persistent chronic irritation, granulation tissue may 
progress into matured RHLs (pyogenic granuloma, 
peripheral ossifying fibroma and peripheral giant cell 
granuloma) which are similar clinically but different 
histopathologically. While some believe they are in 
continuum, others take each as separate entity. Treatment 
is similar in all RHLs but not without recurrence if 
treatment is not properly done. We believe they exist in a 
continuum based on the case findings and therefore 
present a case of infected granulation tissue transforming 
through PG to POF. The objective of study was to report a 
case of infected granulation tissue transitioning through 
pyogenic granuloma into peripheral ossifying fibroma.

Keywords: Reactive Hyperplastic Lesions (RHLs), 
Pyogenic Granuloma (PG), Peripheral ossifying fibroma 
(POF).